2 dead in accident on I-459 South in Hoover (update)

HOOVER, Alabama (UPDATE) -- A Ford Expedition traveling northbound on Interstate 459 in Hoover Tuesday lost control, crossed the median and crashed in the southbound lanes just north of Highway 31, killing two adults and sending two children to the hospital, one of whom with life-threatening injuries, Hoover Police Capt. Jim Coker said. [READ/WATCH: Mountain Brook man, 52, killed in early-morning, 3-vehicle crash on I-459 in Hoover] The single-vehicle accident shut down all southbound lanes, backing up traffic for miles as investigators gathered evidence to determine what caused the wreck. Information regarding the conditions of the two children and the identities of the deceased hasn't been released. Watch ABC 33/40's Focus@4 and the news at 5 and 6 p.m. for the latest on this story. To watch live online, click here. Initial Report: HOOVER, Alabama -- A serious accident with injuries has shut down all southbound lanes of Interstate 459 in Hoover, ABC 33/40 has learned. The crash happened around 1 p.m. just before the Highway 31 exit. At least two people were ejected in the accident and there has been two confirmed fatalities. Hoover police have asked that people please avoid this area, if possible. "If you are on I-459 SB before I-65, avoid the area by exiting onto Acton Road or I-65 then find an alternate route to your destination," police said on Twitter.Several photos showing traffic at a standstill have been posted on Twitter, including the one shown left from Austin Marcum. The cause of the accident is not clear at this time. We'll continue to follow this developing story and provide updates as more information becomes available.To see current traffic conditions, click here.