UAB awarded $19.31 million to lead national study on chronic hypertension in pregnancy

{}The University of Alabama at Birmingham Department of Obstetrics and Gynecology and the Department of Biostatistics have been awarded a $19.31 million R01 grant by the National Institutes of Health's Heart, Lung and Blood Institute to coordinate the most comprehensive study of chronic hypertension in pregnancy ever undertaken.{}The Chronic Hypertension and Pregnancy Project, also known as CHAP, will monitor between 4,700 and 5,700 pregnant women over the next six years, evaluating the benefits and potential harms of pharmacologic treatment of mild chronic hypertension in pregnancy.{}Alan Tita, M.D., Ph.D., professor of obstetrics and gynecology in UAB's School of Medicine and principal investigator/project director for CHAP said, {}"Everyone knows chronic hypertension causes serious and sometimes life-threatening complications for the pregnant woman and her baby, but no one really knows how best to manage the condition during pregnancy. While treatment of chronic hypertension is standard for the general population, it is uncertain whether treatment during pregnancy is beneficial or safe for the fetus. Specifically, while we know chronic hypertension adversely affects the baby's growth, there are concerns that treatment of hypertension may also impair the baby's growth. It's a catch-22, and it's one for which we need to find answers."{}The School of Medicine and the School of Public Health worked for almost three years with the N.H.L.B.I. to plan and fine-tune a study that would help answer this question and others regarding chronic hypertension and pregnancy.{}
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